The cheapest airline(s) flying from Madrid to Lyon is Iberia Express.
Lyon
Two thousand years of history, weaved with modernity and French charm, gives this French city its picturesque, multilayered cityscapes. The Notre-Dame de Fourvière’s glorious facade and interiors and Place des Terreaux’ stately grandeur provide a taste of Lyon’s well-furnished architecture, while the Confluences Museum displays Lyon’s futuristic ambitions. Topped with rich gastronomy supplied by fresh French produce, Les Halles de Lyon introduces you to Lyon’s buffet of renowned gourmet offerings.
Fare Guide for Madrid to Lyon Flights
Estimated lowest fares found within 7 days
Cheapest Airline
Cheapest Month
December
Cheapest Day of the Week
Saturday
Cheapest Time
6pm
Cheapest Airline
Cheapest Month
December
Travel Period: June 2025 - May 2026
The cheapest month(s) to fly from Madrid to Lyon is December.
Cheapest Day of the Week
Saturday
The cheapest day(s) of the week to fly from Madrid to Lyon is Saturday.
Cheapest Time
6pm
The cheapest time of the day to fly from Madrid to Lyon is in the afternoon.
Early Morning 12:01am - 06:00am
Morning 6:01am - 12:00pm
Afternoon 12:01pm - 6:00pm
Evening 6:01pm to 12:00am
12am
6am
12pm
6pm
Top 10 Hotels in Lyon
Sofitel Lyon Bellecour
2e arrondissement
7.8
4896 reviews
Get rates
#1
Hotel Chromatics By Happyculture
2e arrondissement
7.7
6180 reviews
Get rates
#2
Villa Berlioz
2e arrondissement
7.9
2191 reviews
Get rates
#3
Hotel Lyon Charlemagne By Happyculture
2e arrondissement
8.0
6261 reviews
Get rates
#4
Hôtel Lyon Metropole by Arteloge
4e arrondissement
8.0
3900 reviews
Get rates
#5
Appart'city Confort Lyon Cite Internationale
8.1
1873 reviews
Get rates
#6
Résidence Ôtelia Affaires & Bien-être
8e arrondissement
8.0
1521 reviews
Get rates
#7
Mercure Lyon Centre Beaux Arts Hotel
2e arrondissement
8.5
3666 reviews
Get rates
#9
B&b Hotel Lyon Centre Gambetta
3e arrondissement
7.7
8058 reviews
Get rates
#10
ibis Lyon Gerland Rue Mérieux
7e arrondissement
8.0
2007 reviews
Get rates
#11